Irodalom:
* fontos, érdekes közlemény
1. De Moor MH, Posthuma D, Hottenga JJ, és mtsai: Genome-wide linkage scan for exercise participation
in Dutch sibling pairs. Eur J Hum Genet. 2007;15:1252-9.
2.* T Ishii, J Murakami, K Notohara, és mtsai: Oesophageal squamous cell carcinoma may develop within
a background of accumulating DNA methylation in normal and dysplastic mucosa. Gut 2007;56:13-19.
3. Yang SJ, Wang HY, Li XQ, és mtsai: Genetic polymorphisms of ADH2 and ALDH2 association with
esophageal cancer risk in southwest China. World J Gastroenterol 2007; 13: 5760-5764.
4. Tischoff I, Hengge UR, Vieth M, és mtsai: Methylation of SOCS-3 and SOCS-1 in the carcinogenesis
of Barrett’s adenocarcinoma. Gut 2007;56:1047-53.
5. Gazvoda B, Juvan R, Zupanic-Pajnic I, és mtsai: Genetic changes in Slovenian patients with gastric
adenocarcinoma evaluated in terms of microsatellite DNA. EJGH 2007;19:1082-9.
6. Zhang FF, Hou L, Terry MB, és mtsai: Genetic polymorphisms in alcohol metabolism, alcohol intake
and the risk of stomach cancer in Warsaw, Poland. Int J Cancer 2007;121:2060-4.
7. García-González MA, Lanas A, Quintero E, és mtsai: Gastric cancer susceptibility is not linked to pro-and
anti-inflammatory cytokine gene polymorphisms in whites: a Nationwide Multicenter Study in Spain.
Am J Gastroenterol 2007;102:1878-92.
8. Gu H, Yang L, Tang N, és mtsai: Association of endothelin-converting enzyme-1b C-338A polymorphism
with gastric cancer risk: A case-control study. Eur J Cancer 2007 online, PMID: 17977716.
9. Kaisea M, Miwa J, Suzuki N, és mtsai: Inducible nitric oxide synthase gene promoter polymorphism is
associated with increased gastric mRNA expression of inducible nitric oxide synthase and increased
risk of gastric carcinoma EJGH 2007;19:139-45.
10. Szõke D, Molnar B, Solymosi N, és mtsai: T-251A polymorphism of IL-8 relating to the development
of histological gastritis and G-308A polymorphism of TNF-a relating to the development of macroscopic
erosion. EJGH 2007;19:191-5.
11. Koskinen LL, Korponay-Szabo IR, Viiri K, és mtsai: Myosin ixb gene region and gluten intolerance:
linkage to coeliac disease and a putative dermatitis herpetiformis association. J Med Genet 2007 onlina,
PMID: 18077767.
12. Cirillo G, Di Domenico MR, Corsi I, és mtsai: Do MYO9B genetic variants predispose to coeliac disease?
An association study in a cohort of South Italian children. Dig Liver Dis 2007;39:228-31.
13. Latiano A, Mora B, Bonamico M, és mtsai: Analysis of Candidate Genes on chromosomes 5q and 19p
in Celiac Disease. JPGN 2007;45:180-6.
14.* Deleeuw RJ, Zettl A, Klinker E, és mtsai: Whole-Genome Analysis and HLA Genotyping of Enteropathy-
542 Gastro Update 2008
Type T-Cell Lymphoma Reveals 2 Distinct Lymphoma Subtypes. Gastroenterology 2007;132:1902-11.
15.* Vasen HFA, Möslein G, Alonso A, és mtsai: Guidelines for the clinical management of Lynch syndrome
(hereditary non-polyposis cancer). J Med Genet 2007;44:353-62.
16.* Vasen HF, Moeslein G, Alonso A, és mtsai: Guidelines for the clinical management of familial adenomatous
polyposis (FAP). Gut 2008 online, PMID: 18194984.
17. Sulova M,. Zidkova K, Kleibl Z, és mtsai: Mutation analysis of the MYH gene in unrelated Czech APC
mutation-negative polyposis patients. Eur J Cancer 2007;43:1617-21.
18. Hes FJ, Nielsen M, Bik EC, és mtsai: Somatic APC mosaicism: an underestimated cause of polyposis
coli. Gut 2008;57:71-6.
19. Nielsen M, Hes FJ, Nagengast FM és mtsai: Germline mutations in APC and MUTYH are responsible
for the majority of families with attenuated familial adenomatous polyposis. Clin Genet 2007;71:427-33.
20. Baert-Desurmont S, Buisine MP, Bessenay E, és mtsai: Partial duplications of the MSH2 and MLH1
genes in hereditary nonpolyposis colorectal cancer. Eur J Hum Genet 2007;15:383-6.
21. Kastrinos F, Stoffel EM, Balmaña J, és mtsa: Attitudes toward prenatal genetic testing in patients with
familial adenomatous polyposis. Am J Gastroenterol 2007;102:1284-90.
22. Aretz S, Stienen D, Uhlhaas S, és mtsai: High proportion of large genomic deletions and a genotypephenotype
update in 80 unrelated families with juvenile polyposis syndrome. J Med Genet 2007;
44:702-9.
23. Bettstetter M, Dechant S, Ruemmele P, és mtsai: Distinction of Hereditary Nonpolyposis Colorectal
Cancer and SporadicMicrosatellite-Unstable Colorectal Cancer through Quantification of MLH1
Methylation by Real-time PCR. Clin Cancer Res 2007;13:3221-8.
24. Loughrey MB, Waring PM, Tan A, és mtsai: Incorporation of somatic BRAF mutation testing into an
algorithm for the investigation of hereditary non-polyposis colorectal cancer. Familiar Cancer 2007;
6:301-10.
25. Talseth BA, Meldrum C, Suchy J, és mtsai: MDM2 SNP309 T>G alone or in combination with the TP53
R72P polymorphism does not appear to influence disease expression and age of diagnosis of colorectal
cancer in HNPCC patients. Int J Cancer 2007;120:563-5.
26. Papp J, Kovacs ME, Olah E: Germline MLH1 and MSH2 mutational spectrum including frequent large
genomic aberrations in Hungarian hereditary non-polyposis colorectal cancer families: Implications for
genetic testing. World J Gastroenterol 2007; 13: 2727-2732.
27.* Uronis JM, Herfarth HH, Rubinas TC, és mtsai: Flat colorectal cancers are genetically determined and
progress to invasion without going through a polypoid stage. Cancer Res 2007;67:11594-600.
28.* Femia AP, Dolara P, Giannini A, és mtsai: Frequent mutation of Apc gene in rat colon tumors and
mucin-depleted foci, preneoplastic lesions in experimental colon carcinogenesis. Cancer Res 2007;
67:445-9.
29. Grady WM, Ulrich CM: DNA alkylation and DNA methylation: cooperating mechanisms driving the
formation of colorectal adenomas and adenocarcinomas? Gut 2007;56:318-20.
30. Ogino S, Kawasaki T, Kirkner GJ, és mtsai: 18q loss of heterozygosity in microsatellite stable colorectal
cancer is correlated with CpG island methylator phenotype-negative (CIMP-0) and inversely with
CIMP-low and CIMP-high. BMC Cancer. 2007 May 2;7:72.
31. Poynter JN, Figueiredo JC, Conti DV, és mtsai: Variants on 9p24 and 8q24 are associated with risk of
colorectal cancer: results from the Colon Cancer Family Registry. Cancer Res 2007;67:11128-32.
32. Shin SK, Nagasaka T, Jung BH, és mtsai: Epigenetic and Genetic Alterations in Netrin-1 Receptors
Egyéb 543
UNC5C and DCC in Human Colon Cancer. Gastroenterology 2007;133:1849-57.
33. Lin YH, Friederich J, Black MA, és mtsai: Multiple Gene Expression Classifiers from Different Array
Platforms Predict Poor Prognosis of Colorectal Cancer. Clin Cancer Res 2007;13:498-507.
34. Hubner RA, Houlston RS: MTHFR C677T and colorectal cancer risk: a meta-analysis of 25 populations.
Int J Cancer 2007;120:1027-35.
35. Hubner RA, Lubbe S, Chandler I, és mtsai: MTHFR C677T has differential influence on risk of MSI
and MSS colorectal cancer. Hum Mol Genet 2007;16:1072-7.
36. Bethke L, Webb E, Sellick G, és mtsai: Polymorphisms in the cytochrome P450 genes CYP1A2,
CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk. BMC Cancer.
2007 Jul 5;7:123.
37. Gao J, Pfeifer D, He LJ, et al: Association of NFKBIA polymorphism with colorectal cancer risk and
prognosis in Swedish and Chinese populations. Scand J Gastroenterol 2007;42:345-50
38. Lewander A, Butchi AK, Gao J, et al: Polymorphism in the promoter region of the NFKB1 gene increases
the risk of sporadic colorectal cancer in Swedish but not in Chinese populations. Scand J Gastroenterol
2007;42:1332-8.
39.* Jenkins MA, Hayashi S, O’Shea AM, és mtsai: Pathology Features in Bethesda Guidelines Predict
Colorectal Cancer Microsatellite Instability: A Population-Based Study. Gastroenterology 2007;
133:48-56.
40. Malesci A, Laghi L, Bianchi P, és mtsai: Reduced Likelihood of Metastases in Patients with MicrosatelliteUnstable
Colorectal Cancer. Clin Cancer Res 2007;13:3831-9.
41. Slattery ML, Wolff RK, Herrick J, és mtsai: Leptin and leptin receptor genotypes and colon cancer:
Gene-gene and gene-lifestyle interactions. Int J Cancer 2008;122:1611-7.
42. Xing LL, Wang ZN, Jiang L, és mtsai: Matrix metalloproteinase-9-1562C>T polymorphism may increase
the risk of lymphatic metastasis of colorectal cancer. World J Gastroenterol 2007; 13:4626-4629
43. KatoS , Iida S, Higuchi T, és mtsai: PIK3CA mutation is predictive of poor survival in patients with
colorectal cancer. Int J Cancer 2007;121:1771-8.
44. Tuupanen S, Alhopuro P, Mecklin JP, és mtsai: No evidence for association of NOD2 R702W and
G908R with colorectal cancer. Int J Cancer 2007;121:76-9.
45. PL Lakatos, E Hitre, F Szalay, és mtsai: Common NOD2/CARD15 variants are not associated with
susceptibility or the clinicopathologic characteristics of sporadic colorectal cancer in Hungarian
patients. BMC Cancer 2007;7:54.
46.* Xavier RJ, Podolsky DK: Unravelling the pathogenesis of inflammatory bowel disease. Nature 2007;
448:427-43.
47. Rodríguez-Bores L, Fonseca GC, Villeda MA, és mtsai: Novel genetic markers in infl ammatory bowel
disease. World J Gastroenterol 2007; 13: 5560-5570.
48.* The Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of
seven common diseases and 3,000 shared controls. Nature 2007;447:661-78.
49. Tremelling M, Cummings F, Fisher SA, és mtsai: IL23R Variation Determines Susceptibility But Not
Disease Phenotype in Inflammatory Bowel Disease. Gastroenterology 2007;132:1657-64.
50. Cummings JR, Ahmad T, Geremia A, és mtsai: Contribution of the novel inflammatory bowel disease
gene IL23R to disease susceptibility and phenotype. Inflamm Bowel Dis 2007;13: 1063-8.
51. Dubinsky MC, Wang D, Picornell Y és mtsai: IL-23 receptor (IL-23R) gene protects against pediatric
Crohn’s disease. Inflamm Bowel Dis 2007;13:511-5.
544 Gastro Update 2008
52. Weersma RK, Zhernakova A, Nolte IM, és mtsai: ATG16L1 and IL23R Are Associated With Inflammatory
Bowel Diseases but Not With Celiac Disease in The Netherlands. Am J Gastroenterol 2007 online,
PMID: 18047540.
53. Buning C, Schmidt HHJ, Molnar T, és mtsai: Heterozygosity for IL23R p.Arg381Gln confers a protective
effect not only against Crohn’s disease but also ulcerative colitis. Aliment Pharmacol Ther 2007;26:
1025-33.
54. Glas J, Seiderer J, Wetzke M, és mtsai: rs1004819 Is the Main Disease-Associated IL23RVariant in German
Crohn’s disease Patients: Combined Analysis of IL23R, CARD15,and OCTN1/2Variants. PLoS ONE
2007;2:e819.
55.* Neurath MF: IL-23: a master regulator in Crohn’s disease. Nature Med 2007;13:26-28
56.* Hampe J, Franke A, Rosenstiel P és mtsai: A genome-wide association scan of nonsynonymous SNPs
identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 2007;39:207-11.
57. Rioux JD, Xavier RJ, Taylor KD, és mtsai: Genome-wide association study identifies new susceptibility
loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007;39:596-604.
58. Prescott NJ, Fisher SA, Franke A, és mtsai: A nonsynonymous SNP in ATG16L1 predisposes to ileal
Crohn’s disease and is independent of CARD15 and IBD5.Gastroenterology 2007;132:1665-71.
59. Cummings JR, Cooney R, Pathan S, és mtsai: Confirmation of the role of ATG16l1 as a Crohn’s disease
susceptibility gene. Inflamm Bowel Dis. 2007;13:941-6.
60. Roberts RL, Gearry RB, Hollis-Moffatt JE, és mtsai: IL23R R381Q and ATG16L1 T300A Are Strongly
Associated With Crohn’s Disease in a Study of New Zealand Caucasians With Inflammatory Bowel
Disease. Am J Gastroenterol 2007;102:2754-61
61.* Libioulle C, Louis E, Hansoul S, és mtsai: Novel Crohn disease locus identified by genome-wide association
maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet. 2007;3:e58.
62. Silverberg MS, Duerr RH, Brant SR, és mtsai: Refined genomic localization and ethnic differences
observed for the IBD5 association with Crohn’s disease. Eur J Hum Genet 2007;15:328-35.
63. Raelson JV, Little RD, Ruether A, és mtsai: Genome-wide association study for Crohn’s disease in the
Quebec Founder Population identifies multiple validated disease loci. PNAS 2007;104:14747-52.
64.* Parkes M, Barrett JC, Prescott NJ, és mtsai: Sequence variants in the autophagy gene IRGM and multiple
other replicating loci contribute to Crohn’s disease susceptibility. Nat Genet. 2007;39:830-2
65.* Van Limbergen J, Russell RK, Nimmo ER, és mtsa: The genetics of inflammatory bowel disease. Am J
Gastroenterol 2007;102:2820-31.
66. Massey D, Parkes M: Common pathways in Crohn’s disease and other inflammatory diseases revealed
by genomics. Gut 2007;56:1489-92.
67. Dideberg V, Kristjansdottir G, Milani L és mtsai.: An insertion-deletion polymorphism in the Interferon
Regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases. Hum Mol Genet
2007;16:3008-16.
68.* Browning BL, Huebner C, Petermenn I és mtsai.: Has Toll-Like Receptor 4 Been Prematurely Dismissed
as an Inflammatory Bowel Disease Gene? Association Study Combined With Meta-Analysis Shows
Strong Evidence for Association. Am J Gastroenterol 2007; 102:2504-12.
69. Fukuta M, Chen A,. Vamadevan AS, és mtsai.: Toll-Like Receptor-4 Promotes the Development of
Colitis-Associated Colorectal Tumors. Gastroenterology 2007;133:1869-81.
70.* BL Browning, ML Barclay, SA Bingham, és mtsai.: Gender-stratified analysis of DLG5 R30Q in 4707
Crohn’s disease patients and 4973 controls from 12 Caucasian cohorts. J Med Genet 2008;45:36-42.
Egyéb 545
71. Van Limbergen J, Russell RK, Nimmo ER, és mtsai.: Contribution of the NOD1/CARD4 insertion/deletion
polymorphism +32656 to inflammatory bowel disease in Northern Europe. Inflamm Bowel Dis
2007;13:882-9.
72. Molnar T, Hofner P, Nagy F, és mtsai.: NOD1 gene E266K polymorphism is associated with disease
susceptibility but not with disease phenotype or NOD2/CARD15 in Hungarian patients with Crohn’s
disease. Dig Liver Dis 2007;39:1064-70.
73. Kocsis AK, Lakatos PL, Somogyvari F, és mtsai.: Association of ß-defensin 1 Single Nucleotide
Polymorphisms with Crohn’s disease. Scand J Gastroenterol 2007 online, PMID: 17943629
74. Papp M, Altorjay I, Dotan N, és mtsai.: New serological markers for inflammatory bowel disease are
associated with earlier age at onset, complicated disease behavior, risk for surgery, and
NOD2/CARD15 genotype in a Hungarian IBD cohort. Am J Gastroenterol 2007 online, PMID:
18047543
75. Papp M, Altorjay I, Norman GL, és mtsai.: Sero-reactivity to microbial components in Crohn’s disease
is associated with ileal involvement, non-inflammatory disease behaviour and NOD2/CARD15 genotype,
but not with risk for surgery in a Hungarian cohort of IBD patient. Inflamm Bowel Dis 2007;13:984-992.
76. Delvin SM, Yang H, Ippoliti A, és mtsai.: NOD2 Variants and Antibody Response to Microbial Antigens
in Crohn’s Disease Patients and Their Unaffected Relatives. Gastroenterology 2007;132:576-86.
77. Lewis CM, Whitwell SCL, Forbes A,és mtsai.: Estimating risks of common complex diseases across
genetic and environmental factors: the example of Crohn disease. J Med Genet 2007;44:689-94.
78. Konishi K, Shen L, Wang S, és mtsai.: Rare CpG Island Methylator Phenotype in Ulcerative
Colitis-Associated Neoplasias. Gastroenterology 2007;132:1254-60.
79.* Mann CD, Neal CP, Garcea G, és mtsai.: Prognostic molecular markers in hepatocellular carcinoma:
A systematic review. Eur J Cancer 2007;43:979-92.
80.* Nishida N, Nishimura T, Nagasaka T, és mtsai.: Extensive methylation is associated with beta-catenin
mutations in hepatocellular carcinoma: evidence for two distinct pathways of human hepatocarcinogenesis.
Cancer Res 2007;67:4586-94.
81. Yano M, Hamatani K, Eguchi H, és mtsai.: Prognosis in patients with hepatocellular carcinoma correlates
to mutations of p53 and/or hMSH2 genes. Eur J Cancer 2007;43:1092-1100.
82. Lechel A, Holstege H, Begus Y, és mtsai.: Telomerase Deletion Limits Progression of p53-Mutant
Hepatocellular Carcinoma With Short Telomeres in Chronic Liver Disease. Gastroenterology
2007;132:1465-75.
83.* Wurmbach E, Chen YB, Khitrov G, és mtsai.: Genome-wide molecular profiles of HCV-induced
dysplasia and hepatocellular carcinoma. Hepatology 2007;45:938-47.
84. Zhang YJ, Wu HC, Shen J, és mtsai.: Predicting Hepatocellular Carcinoma by Detection of Aberrant
PromoterMethylation in Serum DNA. Clin Cancer Res 2007;13:3278-84
85. Yuan JM, Lu SC, Van Den Berg D, és mtsai.: Genetic polymorphisms in the methylenetetrahydrofolate
reductase and thymidylate synthase genes and risk of hepatocellular carcinoma. Hepatology
2007;46:749-58.
86. Sera T, Hiasa Y, Mashiba T, és mtsai.: Wilms’ tumour 1 gene expression is increased in hepatocellular
carcinoma and associated with poor prognosis. Eur J Cancer 2008 online, PMID: 18255279
87. Abu Al-Soud W, Stenram U, Ljungh A, és mtsai.: DNA of Helicobacter spp. and common gut bacteria
in primary liver carcinoma. Dig Liver Dis 2007;40126-31.
88. Nahon P, Sutton A,Rufat P, és mtsai.: Liver Iron, HFE Gene Mutations, and Hepatocellular Carcinoma
Occurrence in Patients With Cirrhosis. Gastroenterology 2008;134:102-10.
546 Gastro Update 2008
89. Zabala M, Lasarte JJ, Perret C, és mtsai.: Induction of immunosuppressive molecules and regulatory
T cells counteracts the antitumor effect of interleukin-12-based gene therapy in a transgenic mouse
model of liver cancer. J Heaptol 2007;47:807-15.
90. Folmer Y, Schneider M, Blum HE, és mtsa.: Reversal of drug resistance of hepatocellular carcinoma
cells by adenoviral delivery of anti-ABCC2 antisense constructs. Cancer Gene Ther 2007;14:875-84.
91. Dong H, Wang J, Li C, és mtsai.: The phosphatidylethanolamine N-methyltransferase gene V175M single
nucleotide polymorphism confers the susceptibility to NASH in Japanese population. J Hepatol
2007;46:915-20.
92. Tokushige K, Takakura M, Tsuchiya-Matsushita N, és mtsai.: Influence of TNF gene polymorphisms in
Japanese patients with NASH and simple steatosis. J Hepatol 2007;46:1104-10.
93. Nelson JE, Bhattacharya R, Lindor KD és mtsai.: HFE C282Y mutations are associated with advanced
hepatic fibrosis in Caucasians with nonalcoholic steatohepatitis. Hepatology 2007;46:723-9.
94. Schott E, Witt H, Pascu M, és mtsai.: Association of CTLA4 single nucleotide polymorphisms with viral
but not autoimmune liver disease. EJGH 2007;19:947-51.
95. Yokosawa S, Yoshizawa K, Ota M, és mtsai.: A genomewide DNA microsatellite association study of
Japanese patients with autoimmune hepatitis type 1. Hepatology 2007;45:384-90.
96. Schott E, Witt H, Neumann K, és mtsai.: A Toll-like receptor 7 single nucleotide polymorphism protects
from advanced inflammation and fibrosis in male patients with chronic HCV-infection. J Hepatol
2007;47:203-11.
97. Schott E, Witt H, Neumann K, és mtsai.: Association of TLR7 single nucleotide polymorphisms with
chronic HCV-infection and response to interferon-a-based therapy. J Virol 2008;15:71-8.
98. Schott E, Witt H, Hinrichsen H, és mtsai.: Gender-dependent association of CTLA4 polymorphisms
with resolution of hepatitis C virus infection. J Hepatol 2007;46:372-80.
99.* Feld JJ, Nanda S, Huang Y, és mtsai.: Hepatic gene expression during treatment with peginterferon and
ribavirin: Identifying molecular pathways for treatment response. Hepatology 2007;46:1548-63.
100.* Huang H, Shiffman ML, Friedman S, és mtsai.: A 7 gene signature identifies the risk of developing cirrhosis
in patients with chronic hepatitis C. Hepatology 2007;46:297-306.
101. Kraus MR, Al-Taie O, Schafer A, és mtsai.: Serotonin-1A Receptor Gene HTR1A Variation Predicts
Interferon-Induced Depression in Chronic Hepatitis C. Gastroenterology 2007;132:1279-86.
102. Pan QW, Henry SD, Scholte BJ, és mtsai.: New therapeutic opportunities for Hepatitis C based on small
RNA. World J Gastroenterol 2007; 13: 4431-4436.
103. Jiao J, Cao H, Chen XW, és mtsai.: Downregulation of HBx mRNA in HepG2.2.15 cells by small
interfering RNA. EJGH 2007;19:1114-8.
104.* Folhoffer A, Ferenci P, Csak T, és mtsai.: Novel mutations of the ATP7B gene among 109 Hungarian
patients with Wilson’s disease. EJGH 2007;19:105-11.
105. De Bie P, Van De Sluis B, Burstein E, és mtsai.: Distinct Wilson’s Disease Mutations in ATP7B Are
Associated With Enhanced Binding to COMMD1 and Reduced Stability of ATP7B. Gastroenterology
2007;133:1316-26.
106. Gouya L, Muzeau F, Robreau AM, és mtsai.: Genetic Study of Variation in Normal Mouse Iron Homeostasis
Reveals Ceruloplasmin as an HFE-Hemochromatosis Modifier Gene. Gastroenterology 2007;132:
679-86.
107. Asberg A, Hveem K, Kannelønning K, és mtsai.: Penetrance of the C28Y/C282Y genotype of the HFE
gene. Scand J Gastroenterol 2007;42:1073-7.
Egyéb 547
108. Wasmuth HE, Glantz A, Keppeler H, és mtsai.: Intrahepatic cholestasis of pregnancy: the severe form
is associated with common variants of the hepatobiliary phospholipid transporter ABCB4 gene. Gut
2007;56:265-70.
109. Huang YS, Su WJ, Huang YH, és mtsai.: Genetic polymorphisms of manganese superoxide dismutase,
NAD(P)H:quinone oxidoreductase, glutathione S-transferase M1 and T1, and the susceptibility to
drug-induced liver injury. J Heaptol 2007;47:128-34.
110. Zogopoulous G, Rothenmund H, Eppel A, és mtsai.: The P239S palladin variant does not account for a
significant fraction of hereditary or early onset pancreas cancer. Hum Genet 2007;121:635-7.
111. Slater E, Amrillaeva V, Fendrich V, és mtsai.: Palladin mutation causes familial pancreatic cancer:
Absence in European families. PLoS Med 2007;4:e164.
112.* Nakamura T, Kuwai T, Kitadai Y, és mtsai.: Zonal heterogeneity for gene expression in human pancreatic
carcinoma. Cancer Res 2007;67:7597-604.
113. Crous-Bou M, Porta M, López T,és mtsai.: Lifetime history of tobacco consumption and K-ras mutations
in exocrine pancreatic cancer. Pancreas 2007;35:135-41.
114. Jiao L, Zhu J, Hassan MM, és mtsai.: K-ras mutation and p16 and preproenkephalin promoter
hypermethylation in plasma DNA of pancreatic cancer patients: in relation to cigarette smoking.
Pancreas 2007;34:55-62.
115. Jiao L, Bondy ML, Hassan MM, és mtsai.: Glutathione S-transferase gene polymorphisms and risk and
survival of pancreatic cancer. Cancer 2007;109:840-8.
116. Jiao L, Hassan MM, Bondy ML, és mtsai.: XRCC2 and XRCC3 Gene Polymorphism and Risk of
Pancreatic Cancer. Am J Gastroenterol 2007 online, PMID: 17986315.
117. Yu C, Zhang X, Sun G és mtsai.: RNA Interference-Mediated Silencing of the Polo-like Kinase 1 Gene
Enhances Chemosensitivity to Gemcitabine in Pancreatic Adenocarcinoma Cells. J Cell Mol Med. 2008
online, PMID: 18266952.
118. Kiraly O, Wartmann T, Sahin-Toth M.: Missense mutations in pancreatic secretory trypsin inhibitor
(SPINK1) cause intracellular retention and degradation. Gut 2007;56:1433-8.
119. Gao HK, Zhou ZG, Li Y,és mtsai.: Toll-like receptor 4 Asp299Gly polymorphism is associated with an
increased risk of pancreatic necrotic infection in acute pancreatitis: a study in the Chinese population.
Pancreas 2007;34:295-8.
